August 20, 2016
The marketplace for medications is about to get a lot larger. The FDA recent approved the first biosimilar product called Zarxio (filgrastim-sndz) and expects to approve more of them soon.
Associate Director for Therapeutic Biologic Leah Christly, Ph.D., says we need to understand biological products before we can understand biosimilars.
Biologics are medications we make from living organisms. This can include animal, humans or microorganisms like bacteria or yeast. These are different from conventional medications which are usually made from chemicals or are chemically synthesized and have an easy to define structure.
Biologics aren’t made by following a chemical recipe as they come from living organism which vary in nature. These are more complex and not easy to characterize or define. They need a more complex process to manufacturer.
The FDA thoroughly and rigorously evaluates a biologic just like they would do for a regular drug before it gets approval. These biologics are the fasted growing segment of the market for prescription drugs.
A biosimilar is a type of biologic that is very similar to an already FDA approved biologic which is called the reference product. The biosimilar is not just a generic drug. The structure is very complex and it’s not easy to produce as a generic drug. The biosimilar isn’t a copy of another biologic, it’s just very similar to it.
Before any biosimilar is approved by the FDA. It’s verified by experts to make sure there are no clinical meaningful differences between the reference product and the biosimilar.
The biosimilar must also have the same dosage form and strength as well as route of administration as the reference product. The Current Good Manufacturing Practices must be used in the manufacturing of the biosimilar.
FDA approved biosimilars are effective and safe and patients can rely on them. A physician must approve the biosimilar just like they need to approve a biologic. In the marketplace for medications the biosimilar products will create greater competition. This will increase the number of treatment options for patients and lead to less expensive alternative therapies when compared to regular treatments. There are many biosimilars on the market now and consumers get an effective and safe treatment when they use the product at lower costs to them.
January 11, 2016
Almost all mothers go through a period of questioning whether their breast milk supply is adequate, especially when they begin breastfeeding. A mother’s milk supply may diminish temporarily if she’s not feeding her baby often enough because of nipple pain or a poor latch-on technique.
From herbal therapy to prescription medications, there are myriad lactation medications to reestablish milk supply after having taken a lengthy break from nursing, or if a mother feels that her supply isn’t as strong as it once was.
Many mothers have reported overwhelmingly positive responses to breastfeeding milk supply medications, in addition to frequent stimulation of the breast. Mothers typically see an increase in supply within 72 hours. Fenugreek is one of the most common ingredients of breastfeeding milk supply medications; moms have used it for this purpose for hundreds of years. You should see a noticeable increase of your milk supply in one to three days if your body responds to the herb.
December 2, 2015
It doesn’t matter if you’re in your sixties or older, you need to take care with over-the-counter medicines and prescriptions. If you care for older loved ones you have to keep them safe too.
As you get older, the chances that you use more medications increases. This can lead to harmful drug interactions in some cases.
As we get older our bodies can impact the way that we absorb drugs which can lead to harmful complications. The kidneys or live might not work as well as they once did which impacts how the drugs are broken down and removed from the body. The digestive system goes through changes too so the way drugs get to the bloodstream can be impacted.
Deputy director of the Food and Drug Administration (FDA) Office of New Drugs RADM (Ret.) Sandra L. Kweder, M.D., F.A.C.P., says that our physiology changes as we age as we don’t develop many chronic medical conditions until our later years. The normal aging process just leads to changes in the body.
Here are four tips for using medications.
Take the Medicine as Prescribed
Listen to your health care provider and take the medication as it’s prescribed to you. You don’t want to stop taking the medication or skip doses without talking to your health care provider. If you feel better or think the medication isn’t working, you still have to take the medication as prescribed until you can consult with your doctor. If you have problems or side effects that bother you, consult with your provider in these instances too.
Have a Medication List
Keep a list of the medications you take and keep it on your person. Give a copy to your family or another love done that you have trust with. If you travel or have an emergency this list can help health care workers in assisting you.
Record the generic make or the brand name as well as the dosage and how often you take the medication. Make changes to this list when medication changes or dosages go up or down.
Have an Awareness of Potential Interactions
As you get older, you’re more susceptible to drug interactions.
Interactions may occur when:
- One drug impacts how another drug works
- You have a medical condition that makes a certain drug harmful to you
- Non-alcoholic drinks or food reacts with a drug you’re taking
- Alcohol and your medication interact
If you see different health care providers make sure they all know about your supplements as well as medications you take. The pharmacist can also tell you about possible interactions that may occur.
Review all Medications with Your Health Professional
Once a year or more schedule a review of your medications with your health care professional. You need to ensure which ones you have to still take and which one if any, you no longer need.
If a medication you need doesn’t match your budget, see if your health care provider has one that’s cheaper, but still effective and will do the same job.
October 3, 2015
Obesity is something that’s killing more and more people around the world. It doesn’t have to be this way. It can be a thing of the past. Let’s face it. Being overweight isn’t good for anyone. It’s only going to cause you long term health problems. This is why it’s important that you work on losing weight today. You’re not going to want to live the same lifestyle that you have been. The reason for that isn’t just yourself. It’s also for your family. You want to be healthy for them. The only way to do that is by losing weight.
The very first thing you need to do is get up off the couch. People think that to lose weight they need a membership to an expensive gym. That’s not the truth. The best exercise is walking. It doesn’t cost one single red cent to put one foot in front of the other. Get out there and walk at least a half hour per day. Don’t stop at just a half hour. You can walk for an hour or two. Bring your kids along too. They’ll benefit from the exercise. It’ll also help you improve your bond with them. This alone makes it all worthwhile.
Weight Loss Products
Then there are prescription drugs. You’re going to want to think twice about this method of weight loss. As prescription drugs can have side effects. Make sure that you talk to your doctor about all the possible side effects. A good doctor will be upfront with you. They’ll let you know what the side effects are and if the medication is right for you. These can be strong and possibly habit forming drugs. This is why great consideration must be taken before starting any prescription weight loss medication.
There are an ever increasing amount of nonprescription weight loss drugs. These are all natural weight loss medications that don’t require a prescription from a doctor. These can be an effective means for weight loss. All without the harsh side effects of prescription medication. You should make sure to read the labels carefully even when taking natural medications. It’s even a good idea to talk to your doctor before taking them. As some all natural remedies can interact with prescription drugs.
The last thing we’re going to talk about is weight loss surgery. There are several surgical procedures that can be done to help you lose weight. This should be your very last resort. As surgery poses many risks and even death. It’s for this reason that surgery should only be an option for those that are morbidly obese. The risk isn’t worth the reward for the average person that’s just slightly overweight. It’s only for those people who are at least several hundred pounds overweight. Simply put, this is only an option for those who lives are in danger from their obesity.
It should be noted that weight loss isn’t impossible. Even though it can certainly feel like it is. Millions of people around the globe lose weight each and every year. It takes dedication and effort. Find the strength and will to do it from those who you love the most. Never forget they want you around for as long as possible. They only way that’s going to happen is if you lose the weight. Change your life today and never look back. Lose the weight for yourself and those that love you. It’s the best decision you’ll ever make.
February 11, 2015
Regardless of the cause, neuropathy is associated with characteristic symptoms. Although some people with neuropathy may not have symptoms, certain symptoms are common. The degree to which an individual is affected by a particular neuropathy varies.
Damage to the sensory nerves is common in peripheral neuropathy. Symptoms often begin in the feet with a gradual onset of loss of feeling, numbness, tingling, or pain and progress toward the center of the body with time. The arms or legs may be involved. The inability to determine joint position may also occur, which can result in clumsiness or falls. Extreme sensitivity to touch can be another symptom of peripheral neuropathy. The sensation of numbness and tingling of the skin is medically known as paresthesia.
The loss of sensory input from the foot means that blisters and sores on the feet may develop rapidly and not be noticed. Because there is a reduced sensation of pain, these sores may become infected and the infection may spread to deeper tissues, including bone. In severe cases, amputation may be necessary.
Certain prescription medications have been shown to bring relief for those with neuropathy. In severe cases, a combination of medications may be necessary. These drugs may be effective for lessening pain or joint damage and deformities associated with neuropathy, but they should be used with caution because there is some concern that these drugs may worsen nerve injury.
Neuropathy remedies are among those being considered by patients who have had no success with, or do not want the side effects of, pharmaceutical drugs. Natural neuropathy remedies can be safe and effective and can work to promote overall health. Remedies range from herbal and homeopathic to nutritional.